Glutarylcarnitine (lithium)

Glutarylcarnitine (lithium)

• UNSPSC Description: Glutarylcarnitine lithium is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes[1].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/glutarylcarnitine-lithium.html
• Purity: 99.0
• Solubility: DMSO : 1 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : ≥ 100 mg/mL
• Smiles: C[N+](C)(C)C[C@H](OC(CCCC(O[Li])=O)=O)CC([O-])=O
• Molecular Weight: 281.23
• References & Citations: [1]Johnson DW, et al. Stability of malonylcarnitine and Glutarylcarnitine in stored blood spots. J Inherit Metab Dis. 2004;27(6):789-90.|[2]S Tortorelli, et al. The urinary excretion of glutarylcarnitine is an informative tool in the biochemical diagnosis of glutaric acidemia type I. Mol Genet Metab. 2005 Feb;84(2):137-43.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported