Glutarylcarnitine (lithium)

• UNSPSC Description:

  Glutarylcarnitine lithium is the diagnostic metabolite for malonic aciduria and glutaric aciduria type I monitored in most tandem mass spectrometry newborn screening programmes[1].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/glutarylcarnitine-lithium.html

• Purity:

  99.0

• Solubility:

  DMSO : 1 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : ≥ 100 mg/mL

• Smiles:

  C[N+](C)(C)C[C@H](OC(CCCC(O[Li])=O)=O)CC([O-])=O

• Molecular Weight:

  281.23

• References & Citations:

  [1]Johnson DW, et al. Stability of malonylcarnitine and Glutarylcarnitine in stored blood spots. J Inherit Metab Dis. 2004;27(6):789-90.|[2]S Tortorelli, et al. The urinary excretion of glutarylcarnitine is an informative tool in the biochemical diagnosis of glutaric acidemia type I. Mol Genet Metab. 2005 Feb;84(2):137-43.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  No Development Reported