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L-Leucine-d3

CAT: 0804-HY-N0486S9-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0486S9-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
L-Leucine-d3 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
CAS Number
87828-86-2
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; mTOR
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Purity
99.93
Solubility
H2O : ≥ 10 mg/mL
Smiles
[2H]C([2H])([2H])C(C)C[C@H](N)C(O)=O
Molecular Formula
C6H10D3NO2
Molecular Weight
134.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Chemical Information

Leucine 5,5,5-H-2

L-leucine-d3 is a L-leucine and a deuterated compound.

CAS Number87828-86-2
PubChem CID11073472
IUPAC Name(2S)-2-amino-5,5,5-trideuterio-4-methylpentanoic acid
Molecular FormulaC6H13NO2
Molecular Weight134.19
XLogP-1.5
Topological Polar Surface Area63.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Heavy Atom Count9
Formal Charge0
Complexity101
SMILES
[2H]C([2H])([2H])C(C)C[C@@H](C(=O)O)N
InChI
InChI=1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1/i1D3/t4?,5-
InChIKey
ROHFNLRQFUQHCH-LONBSJBQSA-N
Chemical Structure
2D Structure
2D structure of Leucine 5,5,5-H-2
CAS: 87828-86-2
CID: 11073472
Formula: C6H13NO2
MW: 134.19
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight134.19
XLogP3-1.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass134.113458895
Monoisotopic Mass134.113458895
Topological Polar Surface Area63.3 Ų
Heavy Atom Count9
Formal Charge0
Complexity101
Isotope Atom Count3
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes