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Anandamide-d11

CAT: 0804-HY-10863S1Size: 1 mg (1.39 mM x 2 mL in Methanol)Dry Ice: NoHazardous: No
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CAT#:0804-HY-10863S1Size:1 mg (1.39 mM x 2 mL in Methanol)
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Description
Anandamide-d11 is deuterium labeled Anandamide. Anandamide is an immune modulator in the central nervous system acts via not only cannabinoid receptors (CB1 and CB2) but also other targets (e.g., GPR18/GPR55) [1][2].
CAS Number
2260669-86-9
Product Name Alternative
AEA-d11
UNSPSC
12352211
Hazard Statement
H225-H301+H311+H331-H370
Target
Cannabinoid Receptor; Endogenous Metabolite; GPR55; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Concentration
1.39 mM * 2 mL in Methanol
Purity
99
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])/C=C\C/C=C\C/C=C\C/C=C\CCCC(NCCO)=O
Molecular Formula
C22H26D11NO2
Molecular Weight
358.60
Precautions
P210-P233-P240-P241-P242-P243-P260-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P308+P311-P330-P361+P364-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Malek N, et al. Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures. Neural Plast. 2015;2015:130639.|[2]Troy-Fioramonti S, et al. Acute activation of cannabinoid receptors by Anandamide reduces gastrointestinal motility and improves postprandial glycemia in mice. Diabetes. 2015 Mar;64 (3) :808-18.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.
Shipping Conditions
Blue Ice
Storage Conditions
Solution, -20°C, 2 years
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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