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M-PEG4-azide

CAT: 0804-HY-140828-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-140828-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
M-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. m-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
CAS Number
606130-90-9
Product Name Alternative
13-Azido-2,5,8,11-tetraoxatridecane
UNSPSC
12352211
Hazard Statement
H302
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-peg4-azide.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
COCCOCCOCCOCCN=[N+]=[N-]
Molecular Formula
C9H19N3O4
Molecular Weight
233.26
Precautions
H302
References & Citations
[1]Belen Begines, et al. Synthesis of Reduction Sensitive Comb-Like Polyurethanes Using Click Chemistry. Journal of Polymer Science Part A: Polymer Chemistry, 2016, 54 (24), 3888-3900.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers