M-PEG4-azide

• Description:

  M-PEG4-azide (13-Azido-2,5,8,11-tetraoxatridecane) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. m-PEG4-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

• Product Name Alternative:

  13-Azido-2,5,8,11-tetraoxatridecane

• UNSPSC:

  12352211

• Hazard Statement:

  H302

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/m-peg4-azide.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  COCCOCCOCCOCCN=[N+]=[N-]

• Molecular Formula:

  C9H19N3O4

• Molecular Weight:

  233.26

• Precautions:

  H302

• References & Citations:

  [1]Belen Begines, et al. Synthesis of Reduction Sensitive Comb-Like Polyurethanes Using Click Chemistry. Journal of Polymer Science Part A: Polymer Chemistry, 2016, 54 (24), 3888-3900.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PEG Linkers

• CAS Number:

  606130-90-9