Salvinorin A

• UNSPSC Description:

  Salvinorin A is a potent, unique and short-acting high efficacy kappa-opioid receptor (KOPr) agonist with Ki value of 4.3 nm. Salvinorin A is a non-nitrogenous neoclerodane isolated from Salvia divinorum.

• Target Antigen:

  Opioid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/salvinorin-a.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]12[C@]3([H])[C@]([C@@H](C[C@@H](C3=O)OC(C)=O)C(OC)=O)(CC[C@@]1([H])C(O[C@H](C4=COC=C4)C2)=O)C

• Molecular Weight:

  432.46

• References & Citations:

  [1]Butelman ER, et al. Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders. Front Pharmacol. 2015 Sep 8;6:190.|[2]John TF, et al. The antinociceptive effect of salvinorin A in mice.Eur J Pharmacol. 2006 Sep 18;545(2-3):129-33. Epub 2006 Jul 4.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  Phase 1

• CAS Number:

  83729-01-5