Ac-rC Phosphoramidite-13C,d1

Ac-rC Phosphoramidite-13C,d1

• UNSPSC Description: Ac-rC Phosphoramidite-13C,d1 is deuterium and 13C-labeled Ac-rC Phosphoramidite (HY-W042357). Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA).
• Target Antigen: DNA/RNA Synthesis; Isotope-Labeled Compounds
• Type: Isotope-Labeled Compounds
• Related Pathways: Cell Cycle/DNA Damage;Others
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Solubility: 10 mM in DMSO
• Smiles: COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N5C(N=C(NC(C)=O)C([2H])=[13CH]5)=O)O4
• Molecular Weight: 904.10
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Wipapat Kladwang, et al. Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. Biochemistry. 2020 Jun 16;59(23):2154-2170.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported