Products for Research Use Only
RegisterLogin

5- (Hydroxymethyl) cytidine

CAT: 0804-HY-152854-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-152854-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
5- (Hydroxymethyl) cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
CAS Number
19235-17-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others; Cancer
Assay Protocol
https://www.medchemexpress.com/5-hydroxymethyl-cytidine.html
Purity
99.0
Solubility
H2O : 20.83 mg/mL (ultrasonic)
Smiles
NC(C(CO)=CN1[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)=NC1=O
Molecular Formula
C10H15N3O6
Molecular Weight
273.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

Chemical Information

5-Hydroxymethylcytidine

5-Hydroxymethylcytidine is a pyrimidine nucleoside.

CAS Number19235-17-7
PubChem CID14367004
IUPAC Name4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(hydroxymethyl)pyrimidin-2-one
Molecular FormulaC10H15N3O6
Molecular Weight273.24
XLogP-2.7
Topological Polar Surface Area149
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Heavy Atom Count19
Formal Charge0
Complexity437
SMILES
C1=C(C(=NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N)CO
InChI
InChI=1S/C10H15N3O6/c11-8-4(2-14)1-13(10(18)12-8)9-7(17)6(16)5(3-15)19-9/h1,5-7,9,14-17H,2-3H2,(H2,11,12,18)/t5-,6-,7-,9-/m1/s1
InChIKey
NFEXJLMYXXIWPI-JXOAFFINSA-N
Chemical Structure
2D Structure
2D structure of 5-Hydroxymethylcytidine
CAS: 19235-17-7
CID: 14367004
Formula: C10H15N3O6
MW: 273.24
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight273.24
XLogP3-2.7
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count3
Exact Mass273.09608521
Monoisotopic Mass273.09608521
Topological Polar Surface Area149 Ų
Heavy Atom Count19
Formal Charge0
Complexity437
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-1546995- (2-Hydroxyethyl) cytidine
HY-W5555515-Ethyl cytidine
HY-125818-01Cytidine-5'-triphosphate
HY-113400-01Cytidine 5'-diphosphate
HY-W009162-01Cytidine 5'-monophosphate
HY-W400159-015-Methoxy cytidine
HY-145780-01Cytidine 5′-diphosphoethanolamine
HY-W008615-015-Iodo-cytidine
HY-1528695- (Trifluoromethyl) cytidine
HY-1524345-Hydroxymethyl-arauridine

Alternative Products

CatalogName
GTR19215483-015-Hydroxymethyl cytidine
AR-C03953-012'-Deoxy-5- (hydroxymethyl) cytidine
TRC-D512450-250MG2',3'-Dideoxy-3'-(hydroxymethyl)cytidine
434627-015- (Hydroxymethyl) -2',3'-O- (1-methylethylidene) cytidine
TRC-H947115-100MG5-(Hydroxymethyl)-2',3'-O-(1-methylethylidene)cytidine
TRC-D941440-100MG2'-Deoxy-5-(hydroxymethyl)cytidine 5'-(Trihydrogen Diphosphate)
M3400-055- (Methyl-d3) -2’-Deoxy Cytidine (4-Amino-1- (4-hydroxy-5-hydroxymethyl-tetrahydro- furan-2-yl) -5- (methyl-d3) -1H-pyrimidin-2-one)
MBS6057271-015- (Methyl-d3) -2'-Deoxy Cytidine (4-Amino-1- (4-hydroxy-5-hydroxymethyl-tetrahydro- furan-2-yl) -5- (methyl-d3) -1H-pyrimidin-2-one)
301197Cytochlor (5-Chloro-2’-deoxycytidine, 4-amino-5-chloro-1- ((2R,4S,5R) -4- hydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyrimidin- 2 (1H) -one, CIdC, Cytidine, 5-chloro-2'-deoxy) discontinued
B1923-500Cytidine

Popular Products