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5- (2-Hydroxyethyl) cytidine

CAT: 0804-HY-154699Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-154699Size:1 Each
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Description
5- (2-Hydroxyethyl) cytidine is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
CAS Number
137248-64-7
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-2-hydroxyethyl-cytidine.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C=C(CCO)C(N)=NC2=O
Molecular Formula
C11H17N3O6
Molecular Weight
287.27
References & Citations
[1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3 (11) :1062-8.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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