CVS 738

• Description :

  CVS 738 is the desmethyl form of CVS 1123, which is also the major active metabolite of CVS 1123[1][2].

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Assay Protocol :

  https://www.medchemexpress.com/cvs-738.html

• Smiles :

  CCCC(CCC)C(N[C@@H](CC(O)=O)C(N1[C@@H](CCC1)C(N[C@H](C=O)CCCNC(N)=N)=O)=O)=O

• Molecular Formula :

  C23H40N6O6

• Molecular Weight :

  496.60

• References & Citations :

  [1]Mendoza CB, et al. Quantitation of an orally available thrombin inhibitor in rat, monkey and human plasma and in human urine by high-performance liquid chromatography and fluorescent post-column derivatization of arginine. J Chromatogr A. 1997 Feb 21;762 (1-2) :299-310. |[2]Rebello S S, et al. CVS-1123, a direct thrombin inhibitor, prevents occlusive arterial and venous thrombosis in a canine model of vascular injury[J]. Journal of cardiovascular pharmacology, 1997, 29 (2) : 240-249.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [151275-15-9]