Alphadolone acetate

• UNSPSC Description:

  Alphadolone acetate (Alfadolone acetate) is a steroid agent that can suppress or relieve pain, with antinociception[1].

• Target Antigen:

  Others

• Type:

  Reference compound

• Related Pathways:

  Others

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/alphadolone-acetate.html

• Purity:

  98.50

• Solubility:

  DMSO : 250 mg/mL (ultrasonic)

• Smiles:

  C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H](O)CC2)([H])[C@@]4([H])[C@@](C)([C@@H](C(COC(C)=O)=O)CC4)CC3=O

• Molecular Weight:

  390.51

• References & Citations:

  [1]Nadeson R, et al. Antinociceptive properties of neurosteroids II. Experiments with Saffan and its components alphaxalone and alphadolone to reveal separation of anaesthetic and antinociceptive effects and the involvement of spinal cord GABA(A) receptors. Pain. 2000 Oct;88(1):31-39.|[2]Dyer RG, Mansfield S. Anaesthesia with alphaxalone plus alphadolone acetate blocks the oestrogen-stimulated LH surge and impairs pulsatile LH secretion in ovariectomized female rats. J Endocrinol. 1984 Jul;102(1):27-31.|[3]Emanuele MA, et al. Anaesthesia with alphaxalone plus alphadolone acetate decreases serum concentrations of LH in castrated rats. J Endocrinol. 1987 Nov;115(2):221-3.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  23930-37-2