GX-201

• Description:

  GX-201 is a selective NaV1.7 inhibitor, with an IC50 of V1.7[1].

• UNSPSC:

  12352005

• Target:

  Sodium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/gx-201.html

• Purity:

  98.89

• Solubility:

  DMSO : 62.5 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=C(F)C=C(OCC2CCN(CC2)CC3=CC(C(F)(F)F)=CC=C3Cl)C(C4CC4)=C1)NS(=O)(C)=O

• Molecular Formula:

  C25H27ClF4N2O4S

• Molecular Weight:

  563.00

• References & Citations:

  [1]Girish Bankar, et al. Selective Na V 1.7 Antagonists with Long Residence Time Show Improved Efficacy against Inflammatory and Neuropathic Pain. Cell Rep. 2018 Sep 18;24 (12) :3133-3145.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Nav1.7

• CAS Number:

  [1788071-27-1]