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Cornoside

CAT: 0804-HY-N7962-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7962-01Size:1 mg
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Description
Cornoside is a phenolic glycoside and has inhibitory effect on rat lens aldose reductase (AR) with an IC50 of 150 μM[1].
CAS Number
40661-45-8
UNSPSC
12352005
Target
Aldose Reductase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cornoside.html
Purity
96.0
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@H]1O)[C@@H](O[C@@H]([C@H]1O)CO)OCCC(C=CC2=O)(C=C2)O
Molecular Formula
C14H20O8
Molecular Weight
316.30
References & Citations
[1]Hong Mei Li, et al. Analysis of the inhibitory activity of Abeliophyllum distichum leaf constituents against aldose reductase by using high-speed counter current chromatography. Arch Pharm Res. 2013 Sep;36 (9) :1104-12.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Cornoside

Cornoside has been reported in Eurya japonica, Forsythia koreana, and other organisms with data available.

CAS Number40661-45-8
PubChem CID3084796
IUPAC Name4-hydroxy-4-[2-[(2S,3S,4R,5R,6S)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyethyl]cyclohexa-2,5-dien-1-one
Molecular FormulaC14H20O8
Molecular Weight316.30
XLogP-2.1
Topological Polar Surface Area137
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Heavy Atom Count22
Formal Charge0
Complexity444
SMILES
C1=CC(C=CC1=O)(CCO[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)CO)O)O)O)O
InChI
InChI=1S/C14H20O8/c15-7-9-10(17)11(18)12(19)13(22-9)21-6-5-14(20)3-1-8(16)2-4-14/h1-4,9-13,15,17-20H,5-7H2/t9-,10-,11+,12-,13-/m0/s1
InChIKey
VTVARPTUBCBNJX-WJTVCTBASA-N
Chemical Structure
2D Structure
2D structure of Cornoside
CAS: 40661-45-8
CID: 3084796
Formula: C14H20O8
MW: 316.30
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight316.30
XLogP3-2.1
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass316.11581759
Monoisotopic Mass316.11581759
Topological Polar Surface Area137 Ų
Heavy Atom Count22
Formal Charge0
Complexity444
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-N0631-01Cornuside
HY-N10050Coreoside B
HY-N0631RCornuside (Standard)

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CatalogName
BUP20769Cornoside

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