Cornuside (Standard)

CAT: 0804-HY-N0631RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N0631RSize:1 Each
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Description
Cornuside (Standard) is the analytical standard of Cornuside. This product is intended for research and analytical applications. Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases[1].
CAS Number
[131189-57-6]
UNSPSC
12352005
Target
NF-κB; p38 MAPK; Reference Standards
Type
Reference Standards
Related Pathways
MAPK/ERK Pathway; NF-κB; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cornuside-standard.html
Smiles
O=C(C1=CC(O)=C(O)C(O)=C1)OCCC(C(C(OC)=O)=COC2OC(C(C(O)C3O)O)OC3CO)C2C=C
Molecular Formula
C24H30O14
Molecular Weight
542.49
References & Citations
[1]Li L, et al. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Biochem Biophys Res Commun. 2016 Apr 29;473 (2) :408-14.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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