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RASL2 Polyclonal Antibody

CAT: 0749-ABP60100-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60100-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RASA4 (RAS P21 Protein Activator 4) encodes a member of the GAP1 family of GTPase-activating proteins that suppresses the Ras/mitogen-activated protein kinase pathway in response to Ca (2+) . Stimuli that increase intracellular Ca (2+) levels result in the translocation of this protein to the plasma membrane, where it activates Ras GTPase activity. Consequently, Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression, cell growth, and differentiation. Multiple transcript variants encoding different isoforms have been found for RASA4.
Description
Rabbit Anti-RASL2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Ras GTPase-activating protein 4; Calcium-promoted Ras inactivator; Ras p21 protein activator 4; RasGAP-activating-like protein 2
Gene ID
10156
Accession Number
O43374
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human RASL2 protein at amino acid sequence of 100-180
Clonality
Polyclonal
Tag
RASL2
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
88kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RASL2 protein
Observed Molecular Weight
88
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Ras GTPase-activating protein 4; Calcium-promoted Ras inactivator; Ras p21 protein activator 4; RasGAP-activating-like protein 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O43374
Isotype
Rabbit IgG

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