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RASL1 Polyclonal Antibody

CAT: 0749-ABP60099-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP60099-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by RASAL1 (RAS Protein Activator Like 1) is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.
Description
Rabbit Anti-RASL1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
RasGAP-activating-like protein 1; RAS protein activator like 1; Ras GTPase-activating-like protein
Gene ID
8437
Accession Number
O95294
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human RASL1 protein at amino acid sequence of 170-250
Clonality
Polyclonal
Tag
RASL1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
88kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of RASL1 protein
Observed Molecular Weight
88
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
RasGAP-activating-like protein 1; RAS protein activator like 1; Ras GTPase-activating-like protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O95294
Isotype
Rabbit IgG

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