PTPRT Polyclonal Antibody

CAT: 0749-ABP60043-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60043-01Size:30 µL
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Background
The protein encoded by PTPRT is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRT possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. The protein domain structure and the expression pattern of the mouse counterpart of PTPRT suggest its roles in both signal transduction and cellular adhesion in the central nervous system. Two alternatively spliced transcript variants of PTPRT, which encode distinct proteins, have been reported.
Description
Rabbit Anti-PTPRT Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Receptor-type tyrosine-protein phosphatase T; R-PTP-T; Receptor-type tyrosine-protein phosphatase rho; RPTP-rho
Gene ID
11122
Accession Number
O14522
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human PTPRT protein at amino acid sequence of 200-280
Clonality
Polyclonal
Tag
PTPRT
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
158kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PTPRT protein
Observed Molecular Weight
158
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Receptor-type tyrosine-protein phosphatase T; R-PTP-T; Receptor-type tyrosine-protein phosphatase rho; RPTP-rho
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O14522
Isotype
Rabbit IgG

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