PTPRS Polyclonal Antibody

CAT: 0749-ABP60042-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP60042-01Size:30 µL
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Background
The protein encoded by PTPRS is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRS contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. PTPRS has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.
Description
Rabbit Anti-PTPRS Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Receptor-type tyrosine-protein phosphatase S; R-PTP-S; Receptor-type tyrosine-protein phosphatase sigma; R-PTP-sigma
Gene ID
5802
Accession Number
Q13332
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human PTPRS protein at amino acid sequence of 320-400
Clonality
Polyclonal
Tag
PTPRS
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
214kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PTPRS protein
Observed Molecular Weight
214
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Receptor-type tyrosine-protein phosphatase S; R-PTP-S; Receptor-type tyrosine-protein phosphatase sigma; R-PTP-sigma
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q13332
Isotype
Rabbit IgG

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