PTPRS Polyclonal Antibody

• Background:

  The protein encoded by PTPRS is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPRS contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. PTPRS has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

• Description:

  Rabbit Anti-PTPRS Polyclonal Antibody

• Product Name Alternative:

  Receptor-type tyrosine-protein phosphatase S; R-PTP-S; Receptor-type tyrosine-protein phosphatase sigma; R-PTP-sigma

• Gene ID:

  5802

• Accession Number:

  Q13332

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human PTPRS protein at amino acid sequence of 320-400

• Clonality:

  Polyclonal

• Tag:

  PTPRS

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  214kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of PTPRS protein

• Observed Molecular Weight:

  214

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  Receptor-type tyrosine-protein phosphatase S; R-PTP-S; Receptor-type tyrosine-protein phosphatase sigma; R-PTP-sigma

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/Q13332

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG