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PICAL Polyclonal Antibody

CAT: 0749-ABP59907-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59907-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PICALM (Phosphatidylinositol Binding Clathrin Assembly Protein) is a Protein Coding gene. Diseases associated with PICALM include Leukemia, Acute Myeloid and Precursor T-Cell Acute Lymphoblastic Leukemia. Among its related pathways are Clathrin derived vesicle budding and Clathrin-mediated endocytosis. PICALM encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.
Description
Rabbit Anti-PICAL Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Phosphatidylinositol-binding clathrin assembly protein; Clathrin assembly lymphoid myeloid leukemia protein
Gene ID
8301
Accession Number
Q13492
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human PICAL protein at amino acid sequence of 290-370
Clonality
Polyclonal
Tag
PICAL
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
71kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of PICAL protein
Observed Molecular Weight
71
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Phosphatidylinositol-binding clathrin assembly protein; Clathrin assembly lymphoid myeloid leukemia protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q13492
Isotype
Rabbit IgG

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