DSP-4 (hydrochloride)

DSP-4 (hydrochloride)

• CAS Number: 40616-75-9
• UNSPSC Description: DSP-4 hydrochloride is a highly and selective adrenergic neurotoxin. DSP-4 hydrochloride can cross the blood brain barrier. DSP-4 hydrochloride can be used for the temporary selective degradation of the central and peripheral noradrenergic neurons[1][2].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/dsp-4-hydrochloride.html
• Purity: 98.0
• Solubility: DMSO : 125 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
• Smiles: CCN(CCCl)CC1=CC=CC=C1Br.[H]Cl
• Molecular Weight: 313.06
• References & Citations: [1]Hormigo S, et al. The selective neurotoxin DSP-4 impairs the noradrenergic projections from the locus coeruleus to the inferior colliculus in rats. Front Neural Circuits. 2012 Jun 28;6:41.|[2]Jaim-Etcheverry G, et al. DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats. Brain Res. 1980 Apr 28;188(2):513-23.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported