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MYL2 Polyclonal Antibody

CAT: 0749-ABP59368-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59368-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MYL2 (Myosin Light Chain 2) is a Protein Coding gene. Diseases associated with MYL2 include Cardiomyopathy, Hypertrophic, 10 and Congenital Fiber-Type Disproportion. Among its related pathways are Focal Adhesion and Sertoli-Sertoli Cell Junction Dynamics. Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.
Description
Rabbit Anti-MYL2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; MLC-2; MLC-2v
Gene ID
4633
Accession Number
P10916
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from part region of human MYL2 protein at amino acid sequence of 91-140
Clonality
Polyclonal
Tag
MYL2
Applications
WB, ELISA, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
18kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of MYL2
Observed Molecular Weight
18
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Other Product Names
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; MLC-2; MLC-2v
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P10916
Isotype
Rabbit IgG

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