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MRP1 Polyclonal Antibody

CAT: 0749-ABP59326-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP59326-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ABCC1 (ATP Binding Cassette Subfamily C Member 1) is a Protein Coding gene. Diseases associated with ABCC1 include Dubin-Johnson Syndrome and Microsporidiosis. Among its related pathways are Doxorubicin Pathway, Pharmacokinetics and CDK-mediated phosphorylation and removal of Cdc6. The protein encoded by ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.
Description
Rabbit Anti-MRP1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Multidrug resistance-associated protein 1; Leukotriene C (4) transporter; LTC4 transporter; ATP-binding cassette sub-family C member 1
Gene ID
4363
Accession Number
P33527
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human MRP1 protein at amino acid sequence of 110-190
Clonality
Polyclonal
Tag
MRP1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
168kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of MRP1 protein
Observed Molecular Weight
168
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Multidrug resistance-associated protein 1; Leukotriene C (4) transporter; LTC4 transporter; ATP-binding cassette sub-family C member 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P33527
Isotype
Rabbit IgG

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