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MRP3 Polyclonal Antibody

CAT: 0749-ABP51825-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51825-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Canalicular multispecific organic anion transporter 2 (ATP binding cassette subfamily C member 3) encoded by ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . Canalicular multispecific organic anion transporter 2 is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of Canalicular multispecific organic anion transporter 2 has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Description
Rabbit Anti-MRP3 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ABCC3; CMOAT2; MLP2; MRP3; Canalicular multispecific organic anion transporter 2; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3
Gene ID
8714
Accession Number
O15438
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human MRP3 at AA range: 940-1020
Clonality
Polyclonal
Tag
Canalicular multispecific organic anion transporter 2
Applications
WB, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
170kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
MRP3 Polyclonal Antibody detects endogenous levels of MRP3 protein.
Observed Molecular Weight
170
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300
Other Product Names
ABCC3; CMOAT2; MLP2; MRP3; Canalicular multispecific organic anion transporter 2; ATP-binding cassette sub-family C member 3; Multi-specific organic anion transporter D; MOAT-D; Multidrug resistance-associated protein 3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O15438
Isotype
Rabbit IgG

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