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CENPF Polyclonal Antibody

CAT: 0749-ABP58111-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58111-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CENPF (Centromere Protein F) encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association through early anaphase. It localizes to the spindle midzone and the intracellular bridge in late anaphase and telophase, respectively, and is thought to be subsequently degraded. The localization of this protein suggests that it may play a role in chromosome segregation during mitotis. It is thought to form either a homodimer or heterodimer. Autoantibodies against this protein have been found in patients with cancer or graft versus host disease.
Description
Rabbit Anti-CENPF Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Centromere protein F; CENP-F; AH antigen; Kinetochore protein CENPF; Mitosin
Gene ID
1063
Accession Number
P49454
Reactivity
Human
Immunogen
Synthesized peptide derived from part region of human CENPF protein at amino acid sequence of 2190-2270
Clonality
Polyclonal
Tag
CENPF
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
353kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of CENPF protein
Observed Molecular Weight
353
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Centromere protein F; CENP-F; AH antigen; Kinetochore protein CENPF; Mitosin
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P49454
Isotype
Rabbit IgG

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