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CENPJ Polyclonal Antibody

CAT: 0749-ABP58114-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP58114-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CENPJ (Centromere Protein J) encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in CENPJ are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for CENPJ.
Description
Rabbit Anti-CENPJ Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Centromere protein J; CENP-J; Centrosomal P4.1-associated protein; LAG-3-associated protein; LYST-interacting protein 1
Gene ID
55835
Accession Number
Q9HC77
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human CENPJ protein at amino acid sequence of 510-590
Clonality
Polyclonal
Tag
CENPJ
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
147kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of CENPJ protein
Observed Molecular Weight
147
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Centromere protein J; CENP-J; Centrosomal P4.1-associated protein; LAG-3-associated protein; LYST-interacting protein 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9HC77
Isotype
Rabbit IgG

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