CENPR Polyclonal Antibody

CAT: 0749-ABP58122-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP58122-01Size:30 µL
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Background
ITGB3BP (Integrin Subunit Beta 3 Binding Protein) encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. ITGB3BP also acts as a corepressor of NF-kappaB-dependent signaling. ITGB3BP induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. ITGB3BP is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
Description
Rabbit Anti-CENPR Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
Centromere protein R; CENP-R; Beta-3-endonexin; Integrin beta-3-binding protein; Nuclear receptor-interacting factor 3
Gene ID
23421
Accession Number
Q13352
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human CENPR protein at amino acid sequence of 10-90
Clonality
Polyclonal
Tag
CENPR
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
19kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of CENPR protein
Observed Molecular Weight
19
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Centromere protein R; CENP-R; Beta-3-endonexin; Integrin beta-3-binding protein; Nuclear receptor-interacting factor 3
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q13352
Isotype
Rabbit IgG

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