TLE1/2/3/4 Polyclonal Antibody

• Background :

  Transducin-like enhancer of split proteins (TLE1, TLE2, TLE3, TLE4, and TLE6) are mammalian homologs of Drosophila Groucho. TLEs contain several WD-repeats implicated in protein-protein interaction. TLEs are transcriptional co-repressors that bind to many transcription factors such as LEF1, Runx1, Oct-1, hepatocyte nuclear factor 3-β as well as histone H3. TLEs are differentially expressed during animal development and may have overlapping as well as distinct functions.

• Description :

  Rabbit Anti-TLE1/2/3/4 Polyclonal Antibody

• Product Name Alternative :

  Similar to transducin-like enhancer of split 1/2/3/4

• Gene ID :

  7088

• Accession Number :

  Q04724/Q04725/Q04726/Q04727

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from TLE1/2/3/4 at AA range: 721-770

• Clonality :

  Polyclonal

• Tag :

  TLE1

• Applications :

  WB, ELISA, IHC

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  90kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  TLE1/2/3/4 Polyclonal Antibody detects endogenous levels of TLE1/2/3/4.

• Observed Molecular Weight :

  90

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000

• Other Product Names :

  Similar to transducin-like enhancer of split 1/2/3/4

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q04724/Q04725/Q04726/Q04727

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG