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Nodal Polyclonal Antibody

CAT: 0749-ABP57413-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP57413-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NODAL (nodal growth differentiation factor) encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in NODAL are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.
Description
Rabbit Anti-Nodal Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
NODAL; Nodal homolog
Gene ID
4838
Accession Number
Q96S42
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the C-terminal region of human Nodal
Clonality
Polyclonal
Tag
Nodal homolog
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
40kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Nodal Polyclonal Antibody detects endogenous levels of Nodal protein.
Observed Molecular Weight
40
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:10000; IF 1:50-200
Other Product Names
NODAL; Nodal homolog
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q96S42
Isotype
Rabbit IgG

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