UBF Polyclonal Antibody

• Background :

  UBTF (upstream binding transcription factor, RNA polymerase I) encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for UBTF. Pseudogenes of UBTF are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11.

• Description :

  Rabbit Anti-UBF Polyclonal Antibody

• Product Name Alternative :

  UBTF; UBF; UBF1; Nucleolar transcription factor 1; Autoantigen NOR-90; Upstream-binding factor 1; UBF-1

• Gene ID :

  7343

• Accession Number :

  P17480

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from human UBF around the non-phosphorylation site of S484

• Clonality :

  Polyclonal

• Tag :

  Nucleolar transcription factor 1

• Applications :

  WB, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  89kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  UBF Polyclonal Antibody detects endogenous levels of UBF protein.

• Observed Molecular Weight :

  89

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications.

• Other Product Names :

  UBTF; UBF; UBF1; Nucleolar transcription factor 1; Autoantigen NOR-90; Upstream-binding factor 1; UBF-1

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P17480

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG