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Spinosin

CAT: 0804-HY-N0651-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N0651-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Spinosyn is a kind of effective C-saccharide, which has a protective effect. Spinosyn is active through Nrf2/HO-1 pathway inhibition Aβ1-42's production and combination[1][2][3].
CAS Number
72063-39-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Amyloid-β
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/spinosin.html
Purity
99.39
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
COC1=C([C@H](O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H]2O[C@]([C@@H]([C@@H](O)[C@@H]3O)O)([H])O[C@@H]3CO)C(O)=C4C(OC(C5=CC=C(O)C=C5)=CC4=O)=C1
Molecular Formula
C28H32O15
Molecular Weight
608.54
Precautions
H302, H315, H319, H335
References & Citations
[1]Jung IH, et al. Ameliorating effect of spinosin, a C-glycoside flavonoid, on scopolamine-induced memory impairment in mice. Pharmacol Biochem Behav. 2014 May;120:88-94.|[2]Xu F, et al. Neuroprotective Effects of Spinosin on Recovery of Learning and Memory in a Mouse Model of Alzheimer's Disease. Biomol Ther (Seoul) . 2019 Jan 1;27 (1) :71-77.|[3]Zhang X, et al. Spinosin Inhibits Aβ1-42 Production and Aggregation via Activating Nrf2/HO-1 Pathway. Biomol Ther (Seoul) . 2019 Dec 3.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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