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KOR-1 Polyclonal Antibody

CAT: 0749-ABP55446-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP55446-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in OPRK1 have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
Description
Rabbit Anti-KOR-1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1
Gene ID
4986
Accession Number
P41145
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthesized peptide derived from the C-terminal region of human KOR-1 at AA range: 290-370
Clonality
Polyclonal
Tag
Kappa-type opioid receptor
Applications
WB, ELISA, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
48kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
KOR-1 Polyclonal Antibody detects endogenous levels of KOR-1 protein.
Observed Molecular Weight
48
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000
Other Product Names
OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P41145
Isotype
Rabbit IgG

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