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KOR-1 Polyclonal Antibody

CAT: 0965-JOT-AP04856-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP04856-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
OPRK1 encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in OPRK1 have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
CAS Number
9007-83-4
Synonyms
OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1
Host
Rabbit
Reactivity
Mouse;Rat
Immunogen
The antiserum was produced against synthesized peptide derived from mouse KOR-1. AA range:331-380
Clonality
Polyclonal
Applications
IHC-p, WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
42645
Antibody Type
Primary antibody
Isotype
IgG

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