SR-1B Polyclonal Antibody

CAT: 0749-ABP54800-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP54800-01Size:30 µL
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Background
The 5-hydroxytryptamine receptor 1B encoded by HTR1B is a G-protein coupled receptor for serotonin (5-hydroxytryptamine) . Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs.
Description
Rabbit Anti-SR-1B Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
HTR1B; HTR1DB; 5-hydroxytryptamine receptor 1B; 5-HT-1B; 5-HT1B; S12; Serotonin 1D beta receptor; 5-HT-1D-beta; Serotonin receptor 1B
Gene ID
3351
Accession Number
P28222
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human SR-1B at AA rangle: 180-260
Clonality
Polyclonal
Tag
5-hydroxytryptamine receptor 1B
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
43kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
SR-1B Polyclonal Antibody detects endogenous levels of SR-1B protein.
Observed Molecular Weight
43
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
HTR1B; HTR1DB; 5-hydroxytryptamine receptor 1B; 5-HT-1B; 5-HT1B; S12; Serotonin 1D beta receptor; 5-HT-1D-beta; Serotonin receptor 1B
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P28222
Isotype
Rabbit IgG

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