SR-3D Polyclonal Antibody

• Background :

  The 5-hydroxytryptamine receptor 3D encoded HTR3D belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• Description :

  Rabbit Anti-SR-3D Polyclonal Antibody

• Product Name Alternative :

  HTR3D; 5-hydroxytryptamine receptor 3D; 5-HT3-D; 5-HT3D; Serotonin receptor 3D

• Gene ID :

  200909

• Accession Number :

  Q70Z44

• Reactivity :

  Human

• Immunogen :

  Synthesized peptide derived from the N-terminal region of human SR-3D at AA rangle: 10-90

• Clonality :

  Polyclonal

• Tag :

  5-hydroxytryptamine receptor 3D

• Applications :

  WB, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  50kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  SR-3D Polyclonal Antibody detects endogenous levels of SR-3D protein.

• Observed Molecular Weight :

  50

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.

• Other Product Names :

  HTR3D; 5-hydroxytryptamine receptor 3D; 5-HT3-D; 5-HT3D; Serotonin receptor 3D

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/Q70Z44

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG