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Dok-7 Polyclonal Antibody

CAT: 0749-ABP54610-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP54610-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The docking protein 7 encoded by DOK7 is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in DOK7 are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-Dok-7 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
DOK7; C4orf25; Protein Dok-7; Downstream of tyrosine kinase 7
Gene ID
285489
Accession Number
Q18PE1
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human Dok-7 at AA rangle: 10-90
Clonality
Polyclonal
Tag
Protein Dok-7
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
60kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Dok-7 Polyclonal Antibody detects endogenous levels of Dok-7 protein.
Observed Molecular Weight
60
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
DOK7; C4orf25; Protein Dok-7; Downstream of tyrosine kinase 7
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q18PE1
Isotype
Rabbit IgG

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