Dok-2 Polyclonal Antibody

CAT: 0749-ABP51192-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP51192-01Size:30 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Docking protein 2 encoded by DOK2 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 2 binds p120 (RasGAP) from CML cells.
Description
Rabbit Anti-Dok-2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56 (dok-2)
Gene ID
9046
Accession Number
O60496
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human Dok-2 around the non-phosphorylation site of Y299
Clonality
Polyclonal
Tag
Docking protein 2
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
46kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Dok-2 Polyclonal Antibody detects endogenous levels of Dok-2 protein.
Observed Molecular Weight
46
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
DOK2; Docking protein 2; Downstream of tyrosine kinase 2; p56 (dok-2)
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/O60496
Isotype
Rabbit IgG

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