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Dok-5 Polyclonal Antibody

CAT: 0965-JOT-AP02701-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP02701-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by DOK5 (docking protein 5) is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of DOK5 results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
DOK5; C20orf180; Docking protein 5; Downstream of tyrosine kinase 5; Insulin receptor substrate 6; IRS-6; IRS6
Host
Rabbit
Reactivity
Human;Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human DOK5. AA range:101-150
Clonality
Polyclonal
Applications
WB, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
35464
Antibody Type
Primary antibody
Isotype
IgG