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14-3-3 σ Polyclonal Antibody

CAT: 0749-ABP54573-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP54573-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SFN (Stratifin) is a Protein Coding gene. Diseases associated with SFN include pancreatic ductal adenocarcinoma and limbal stem cell deficiency. Among its related pathways are Gene Expression and Signaling by GPCR. GO annotations related to this gene include protein kinase binding and phosphoprotein binding. An important paralog of this gene is YWHAZ. dapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53. 53-regulated inhibitor of G2/M progression.
Description
Rabbit Anti-14-3-3 σ Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin
Gene ID
2810
Accession Number
P31947
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human 14-3-3 σ at AA rangle: 10-90
Clonality
Polyclonal
Tag
14-3-3 protein sigma
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
30kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
14-3-3 σ Polyclonal Antibody detects endogenous levels of 14-3-3 σ protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300; WB 1:500-1:2000; ELISA 1:20000; IF 1:50-200
Other Product Names
SFN; HME1; 14-3-3 protein sigma; Epithelial cell marker protein 1; Stratifin
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P31947
Isotype
Rabbit IgG

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