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EpoR Polyclonal Antibody

CAT: 0749-ABP54139-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP54139-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
Description
Rabbit Anti-EpoR Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
EPOR; Erythropoietin receptor; EPO-R
Gene ID
2057
Accession Number
P19235
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthesized peptide derived from human EpoR around the non-phosphorylation site of Y368
Clonality
Polyclonal
Tag
Erythropoietin receptor
Applications
WB, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
65kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
EpoR Polyclonal Antibody detects endogenous levels of EpoR protein.
Observed Molecular Weight
65
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
EPOR; Erythropoietin receptor; EPO-R
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P19235
Isotype
Rabbit IgG

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