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EpoR Polyclonal Antibody

CAT: 0965-JOT-AP03025-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP03025-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.
CAS Number
9007-83-4
Synonyms
EPOR; Erythropoietin receptor; EPO-R
Host
Rabbit
Reactivity
Human;Mouse;Rat;Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human Epo-R. AA range:341-390
Clonality
Polyclonal
Applications
WB, IF, ELISA
Stability
-20°C for one year
Concentration
1 mg/ml
Molecular Weight
55065
Antibody Type
Primary antibody
Isotype
IgG

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