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PWWP2B Polyclonal Antibody

CAT: 0749-ABP53999-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53999-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PWWP2B (PWWP domain containing 2B) is a 590 amino acid protein that contains a PWWP domain which is involved in protein-protein interactions. The PWWP2B protein is phosphorylated upon DNA damage, probably by Atm or ATR. The PWWP2B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 10q26. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4. % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Description
Rabbit Anti-PWWP2B Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
PWWP2B; PWWP2; PWWP domain-containing protein 2B
Gene ID
170394
Accession Number
Q6NUJ5
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human PWWP2B at AA rangle: 240-320
Clonality
Polyclonal
Tag
PWWP domain-containing protein 2B
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
64kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
PWWP2B Polyclonal Antibody detects endogenous levels of PWWP2B protein.
Observed Molecular Weight
64
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
PWWP2B; PWWP2; PWWP domain-containing protein 2B
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q6NUJ5
Isotype
Rabbit IgG

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