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HMG-1 Polyclonal Antibody

CAT: 0749-ABP53233-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP53233-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HMGB1 encodes high mobility group box 1 that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.
Description
Rabbit Anti-HMG-1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
Gene ID
3146
Accession Number
P09429
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human HMG-1
Clonality
Polyclonal
Tag
High mobility group protein B1
Applications
IF, WB, IHC, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
30kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
HMG-1 Polyclonal Antibody detects endogenous levels of HMG-1 protein.
Observed Molecular Weight
25
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200; WB 1:500-1:2000; IHC: 1:100-1:300; ELISA 1:20000; Not yet tested in other applications
Other Product Names
HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P09429
Isotype
Rabbit IgG

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