Products for Research Use Only

HMG-2 Polyclonal Antibody

CAT: 0749-ABP51541-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51541-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that high mobility group protein B2 is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V (D) J recombination.
Description
Rabbit Anti-HMG-2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2; HMG-2
Gene ID
3148
Accession Number
P26583
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human HMG-2 at AA range: 100-180
Clonality
Polyclonal
Tag
High mobility group protein B2
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
27kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
HMG-2 Polyclonal Antibody detects endogenous levels of HMG-2 protein.
Observed Molecular Weight
27
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2; HMG-2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P26583
Isotype
Rabbit IgG

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