ET-1 Polyclonal Antibody

CAT: 0749-ABP52878-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP52878-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
EDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-ET-1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
EDN1; Endothelin-1; Preproendothelin-1; PPET1
Gene ID
1906
Accession Number
P05305
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human ET-1
Clonality
Polyclonal
Tag
Endothelin-1
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
25kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
ET-1 Polyclonal Antibody detects endogenous levels of ET-1 protein.
Observed Molecular Weight
25
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300; WB 1:500-1:2000; ELISA 1:20000; IF 1:50-200
Other Product Names
EDN1; Endothelin-1; Preproendothelin-1; PPET1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P05305
Isotype
Rabbit IgG

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