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Rac GAP1 Polyclonal Antibody

CAT: 0749-ABP52300-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP52300-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RACGAP1 encodes a GTPase-activating protein (GAP) that is a compoment of the centralspindlin complex. Rac GTPase activating protein 1 binds activated forms of Rho GTPases and stimulates GTP hydrolysis, which results in negative regulation of Rho-mediated signals. Rac GTPase activating protein 1 plays a regulatory role in cytokinesis, cell growth, and differentiation. Alternatively spliced transcript variants have been found for RACGAP1. There is a pseudogene for RACGAP1 on chromosome 12.
Description
Rabbit Anti-Rac GAP1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
RACGAP1; KIAA1478; MGCRACGAP; Rac GTPase-activating protein 1; Male germ cell RacGap; MgcRacGAP; Protein CYK4 homolg; CYK4; HsCYK-4
Gene ID
29127
Accession Number
Q9H0H5
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthesized peptide derived from human Rac GAP1 around the non-phosphorylation site of S387
Clonality
Polyclonal
Tag
Rac GTPase-activating protein 1
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
72kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Rac GAP1 Polyclonal Antibody detects endogenous levels of Rac GAP1 protein.
Observed Molecular Weight
72
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
RACGAP1; KIAA1478; MGCRACGAP; Rac GTPase-activating protein 1; Male germ cell RacGap; MgcRacGAP; Protein CYK4 homolg; CYK4; HsCYK-4
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9H0H5
Isotype
Rabbit IgG

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