RAC2 Polyclonal Antibody

• Background:

  RAC2 (Rac Family Small GTPase 2) encodes a member of the Ras superfamily of small guanosine triphosphate (GTP) -metabolizing proteins. The encoded protein localizes to the plasma membrane, where it regulates diverse processes, such as secretion, phagocytosis, and cell polarization. Activity of this protein is also involved in the generation of reactive oxygen species. Mutations in RAC2 are associated with neutrophil immunodeficiency syndrome. There is a pseudogene for RAC2 on chromosome 6.

• Description:

  Rabbit Anti-RAC2 Polyclonal Antibody

• Product Name Alternative:

  Ras-related C3 botulinum toxin substrate 2; GX; Small G protein; p21-Rac2

• Gene ID:

  5880

• Accession Number:

  P15153

• Reactivity:

  Human, Mouse, Bovine, Bovine

• Immunogen:

  Synthesized peptide derived from part region of human RAC2 protein at amino acid sequence of 130-210

• Clonality:

  Polyclonal

• Tag:

  RAC2

• Applications:

  WB, ELISA

• Purification Method:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Molecular Weight:

  21kD

• Precautions:

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions:

  Gel pack with blue ice.

• Storage Conditions:

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes:

  The antibody detects endogenous levels of RAC2 protein

• Observed Molecular Weight:

  21

• Formulation:

  Liquid solution

• Buffer pH:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Applications Notes:

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

• Other Product Names:

  Ras-related C3 botulinum toxin substrate 2; GX; Small G protein; p21-Rac2

• Tested Applications:

  WB, IHC, IF, IP, ELISA

• Host or Source:

  Rabbit

• Accession Number URL:

  http://www.uniprot.org/uniprot/P15153

• CAS Number:

  9007-83-4

• Isotype:

  Rabbit IgG