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MLH1 Polyclonal Antibody

CAT: 0749-ABP51798-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51798-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC) . It is a human homolog of the E.coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
Description
Rabbit Anti-MLH1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
Gene ID
4292
Accession Number
P40692
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human MLH1 at AA range: 410-490
Clonality
Polyclonal
Tag
DNA mismatch repair protein Mlh1
Applications
WB, IHC
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
85kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
MLH1 Polyclonal Antibody detects endogenous levels of MLH1 protein.
Observed Molecular Weight
85
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300
Other Product Names
MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P40692
Isotype
Rabbit IgG

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