MGluR5 Polyclonal Antibody

• Background :

  GRM5 encodes a member of the G-protein coupled receptor 3 protein family. Metabotropic glutamate receptor 5 is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. Metabotropic glutamate receptor 5 may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.

• Description :

  Rabbit Anti-mGluR5 Polyclonal Antibody

• Product Name Alternative :

  GRM5; GPRC1E; MGLUR5; Metabotropic glutamate receptor 5; mGluR5

• Gene ID :

  2915

• Accession Number :

  P41594

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from the N-terminal region of human mGluR5 at AA range: 40-120

• Clonality :

  Polyclonal

• Tag :

  Metabotropic glutamate receptor 5

• Applications :

  WB, IHC, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  130kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  MGluR5 Polyclonal Antibody detects endogenous levels of mGluR5 protein.

• Observed Molecular Weight :

  130

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.

• Other Product Names :

  GRM5; GPRC1E; MGLUR5; Metabotropic glutamate receptor 5; mGluR5

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P41594

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG