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MGluR5 Polyclonal Antibody

CAT: 0749-ABP51787-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51787-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
GRM5 encodes a member of the G-protein coupled receptor 3 protein family. Metabotropic glutamate receptor 5 is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. Metabotropic glutamate receptor 5 may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.
Description
Rabbit Anti-mGluR5 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
GRM5; GPRC1E; MGLUR5; Metabotropic glutamate receptor 5; mGluR5
Gene ID
2915
Accession Number
P41594
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the N-terminal region of human mGluR5 at AA range: 40-120
Clonality
Polyclonal
Tag
Metabotropic glutamate receptor 5
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
130kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
MGluR5 Polyclonal Antibody detects endogenous levels of mGluR5 protein.
Observed Molecular Weight
130
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
GRM5; GPRC1E; MGLUR5; Metabotropic glutamate receptor 5; mGluR5
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P41594
Isotype
Rabbit IgG

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