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Oxolinic acid (Standard)

CAT: 0804-HY-B1002R-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1002R-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oxolinic acid (Standard) is the analytical standard of Oxolinic acid. This product is intended for research and analytical applications. Oxolinic acid is an antibiotic against both Gram-negative and Gram-positive bacteria. Oxolinic acid can be used for the research of acute and chronic urinary tract infections. Oxolinic acid is a DNA/RNA synthesis inhibitor. Oxolinic acid acts a dopamine uptake inhibitor and stimulants locomotor effect in mice[1][2][3].
CAS Number
14698-29-4
UNSPSC
12352005
Hazard Statement
H302
Target
Antibiotic; Bacterial; DNA/RNA Synthesis; Reference Standards
Type
Reference Standards
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Others
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/oxolinic-acid-standard.html
Purity
97.60
Solubility
H2O : < 0.1 mg/mL
Smiles
O=C(C1=CN(CC)C2=C(C=C3C(OCO3)=C2)C1=O)O
Molecular Formula
C13H11NO5
Molecular Weight
261.23
Precautions
H302
References & Citations
[1]M J Kershaw, et al. The antibacterial and pharmacological activity of oxolinic acid (Prodoxol) . J Antimicrob Chemother. 1975 Sep;1 (3) :311-5.|[2]S H Manes, et al. Inhibition of RNA synthesis by oxolinic acid is unrelated to average DNA supercoiling. J Bacteriol. 1983 Jul; 155 (1) : 420-423.|[3]J Garcia de Mateos-Verchere, et al. Behavioural and neurochemical evidence that the antimicrobial agent oxolinic acid is a dopamine uptake inhibitor. Eur Neuropsychopharmacol. 1998 Dec;8 (4) :255-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported

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