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HDAC8 Polyclonal Antibody

CAT: 0749-ABP51507-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51507-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 8 encoded by HDAC8 belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for HDAC8.
Description
Rabbit Anti-HDAC8 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8
Gene ID
55869
Accession Number
Q9BY41
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthesized peptide derived from human HDAC8 around the non-phosphorylation site of S39
Clonality
Polyclonal
Tag
Histone deacetylase 8
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
42kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
HDAC8 Polyclonal Antibody detects endogenous levels of HDAC8 protein.
Observed Molecular Weight
42
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9BY41
Isotype
Rabbit IgG

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